atrasentan

Product Name: atrasentan
CAS No.: 173937-91-2
Chemical Name: atrasentan
Synonyms: A-147627;atrasentan;(+)-A 127722;(+)-A 127722;Atrasentan (ABT-627);A127722, CID 5310990;(+)-A 127722; ABT-627; A 127722; ABT 627;Atrasentan,Endothelin Receptor,A 147627,ABT627,Inhibitor,inhibit,A147627,ABT 627;(2R,3R,4S)-4-(1,3-Benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)pyrrolidine-3-carboxylic acid;(2S,3S,4R)-4-(1,3-BENZODIOXOL-5-YL)-1-[2-(DIBUTYLAMINO)-2-OXOETHYL]-2-(4-METHOXYPHENYL)PYRROLIDINE-3-CARBOXYLIC ACID
CBNumber: CB91320566
Molecular Formula: C29H38N2O6
Formula Weight: 510.62
MOL File: 173937-91-2.mol

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atrasentan Property

Melting point:: 122-124°
Boiling point:: 659.4±55.0 °C(Predicted)
Density: 1.188±0.06 g/cm3(Predicted)
storage temp.: -20°C Freezer, Under inert atmosphere
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
pka: 3.49±0.60(Predicted)
color: Off-White

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: A793925
Product name: Atrasentan
Packaging: 25mg
Price: $745
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0005136
Product name: ATRASENTAN
Purity: 95.00%
Packaging: 5MG
Price: $550
Updated: 2021/12/16

CSNpharm

Product number: CSN18015
Product name: Atrasentan
Packaging: 50mg
Price: $784
Updated: 2021/12/16

CSNpharm

Product number: CSN18015
Product name: Atrasentan
Packaging: 5mg
Price: $242
Updated: 2021/12/16

Crysdot

Product number: CD31002983
Product name: Atrasentan
Purity: 98+%
Packaging: 5mg
Price: $250
Updated: 2021/12/16

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atrasentan Chemical Properties,Usage,Production

Uses

Palliative treatment of bone pain due to metastatic prostate cancer and disease progression (endothelin (ETA) receptor antagonist).

Uses

Atrasentan is a selective antagonist of the endothelin-A (ETA) receptor and binds selectively to the ETA receptor, which may result in inhibition of endothelin-induced angiogenesis and tumor cell proliferation.

Definition

ChEBI: Atrasentan is a member of pyrrolidines.

atrasentan Preparation Products And Raw materials

Raw materials

Preparation Products

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atrasentan Suppliers

China 57 India 1 United Kingdom 1 United States 5 Global 64

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View Lastest Price from atrasentan manufacturers

Career Henan Chemical Co

Product: atrasentan 173937-91-2
Price: US $0.01/KG
Min. Order: 1KG
Purity: 98%; 99%
Supply Ability: 500g;1kg； 25kg
Release date: 2020-01-09

173937-91-2, atrasentanRelated Search:

tert-Butyl ethyl ether Aspartame Benzo[a]pyrene Selenium dioxide DIOXOPROMETHAZINE HCL 1,4-Dioxane 2-(2-Aminoethylamino)ethanol atrasentan

atrasentan

(2R,3R,4S)-4-(1,3-Benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)pyrrolidine-3-carboxylic acid

(+)-A 127722

A-147627

(2R,3R,4S)-4-(1,3-Benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)-3-pyrrolidinecarboxylic acid

(2S,3S,4R)-4-(1,3-BENZODIOXOL-5-YL)-1-[2-(DIBUTYLAMINO)-2-OXOETHYL]-2-(4-METHOXYPHENYL)PYRROLIDINE-3-CARBOXYLIC ACID

A127722, CID 5310990

Atrasentan (ABT-627)

(+)-A 127722; ABT-627; A 127722; ABT 627

Atrasentan [2R,3R,4S]-2-(4-methoxyphenyl)-4-(1,3-benzodioxol-5-yl)-1-[[(N,N-dibutylamino)-carboxyl]methyl]pyrrolidine-3-carboxylic acid

3-Pyrrolidinecarboxylic acid, 4-(1,3-benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)-, (2R,3R,4S)-

(2R,3R,4S)-4-(Benzod1,3dioxol-5-yl)-1-(2-(dibutylamino)-2-oxoethyl)-2-(4-methoxyphenyl)pyrrolidine-3-carboxylic acid.HCl

(+)-A 127722

Atrasentan,Endothelin Receptor,A 147627,ABT627,Inhibitor,inhibit,A147627,ABT 627

173937-91-2

API